SGLT2 Inhibition and Diabetes - Video
This video resource explores the mechanism of action of SGLT2 inhibition in a kidney with type 1 or type 2 diabetes.
What you'll learn:
- How SGLT2 inhibition prevents glucose and sodium reabsorption in the proximal tubule, leading to glycosuria and a lowering in plasma glucose
- How preventing sodium uptake may restore sodium delivery to the macula densa and activate tubulo-glomerular feedback (TGF)
- The results of two studies into SGLT2 inhibition amongst diabetes patients, one of young adults with type 1 diabetes and one of older patients with type 2 diabetes
This resource has been reviewed for consistency with FDA guidelines and is not approved for continuing medical education credit.
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