Kidney and DKD Pathophysiology - Video

This video resource explores the function of the kidneys and visualizes the changes in structure and physiological regulatory mechanisms in diabetic kidney disease (DKD).

What you'll learn:

• How the kidneys autoregulate to ensure a regular intraglomerular pressure
• The two main regulatory mechanisms that control intraglomerular pressure
• The effect of diabetes on the glomerulus, including an increase in the reabsorption of glucose and sodium
• What happens in the kidneys when the body enters a condition of hyperglycemia, including:
  • Failure of the physiological regulation of intraglomerular pressure through the tubulo-glomerular feedback (TGF) mechanism
  • Rising intraglomerular pressure following the failure of the TGF mechanism
• How the failure of the TGF mechanism, along with an increase in intraglomerular pressure, can contribute to the development of diabetic nephropathy

This resource has been reviewed for consistency with FDA guidelines and is not approved for continuing medical education credit.