Utilization of HIV Drug Resistance Testing in Treatment Experienced Patients (UTILIZE Study)

Inclusion criteria

Patients that meet the following inclusion criteria will be eligible for participation in this study:

1. Signed patient informed consent prior to study participation.

2. HIV-1 infected male or female ?18 years of age.

3. Have confirmed (2 consecutive) HIV RNA ?1000 copies/mL (one of the results must be within 3 months of enrollment into the study).

4. Current HAART regimen contains a protease inhibitor for ?3 months.

5. Physicians considering a change in the patient?s HAART regimen. f.) History of treatment with 2 or more protease inhibitors (including the current PI). Low dose ritonavir (i.e.\< 400 mg. bid) is not counted as one of the PIs.

Exclusion criteria

A patient with any of the following criteria will be excluded from participation in the study:

1. ARV medication naive.

2. Active opportunistic infection. c.) Known or suspected non-adherence to current HAART regimen as assessed by the investigator.