Pulmonary Fibrosis and PDE4B – Video

Discover the pathophysiology of pulmonary fibrosis.

What you'll learn:

• Which patients may develop pulmonary fibrosis.
• The inflammatory and fibrotic mechanisms that contribute to the pathogenesis and progression of pulmonary fibrosis, including:
  • how an initial injury to the epithelium can trigger an abnormal healing response
  • how recurring injury results in a proinflammatory and profibrotic milieu and develops into a self-sustaining process of inflammation and fibrosis.
• Current therapeutic targets for pulmonary fibrosis, including phosphodiesterase 4 (PDE4).
• The effects of PDE4 inhibition on epithelial cells, microphages, and fibroblasts.
• Potential side effects of PDE4 inhibition and their impact on the efficacy of potential therapeutic treatments.