Pulmonary Fibrosis and PDE4B – Video
Pulmonary Fibrosis and PDE4B – Video
Discover the pathophysiology of pulmonary fibrosis.
What you'll learn:
- Which patients may develop pulmonary fibrosis.
- The inflammatory and fibrotic mechanisms that contribute to the pathogenesis and progression of pulmonary fibrosis, including:
- how an initial injury to the epithelium can trigger an abnormal healing response
- how recurring injury results in a proinflammatory and profibrotic milieu and develops into a self-sustaining process of inflammation and fibrosis.
- Current therapeutic targets for pulmonary fibrosis, including phosphodiesterase 4 (PDE4).
- The effects of PDE4 inhibition on epithelial cells, microphages, and fibroblasts.
- Potential side effects of PDE4 inhibition and their impact on the efficacy of potential therapeutic treatments.
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