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For US Healthcare Professionals Only

Review the pathophysiology of cells according to autoimmune and autoinflammatory diseases. This video includes a clear visual demonstration of the differences in pustule formation in clinical types of psoriasis including generalized pustular psoriasis (GPP).

What you'll learn:

  • The role of keratinocytes in protecting the body from the external environment
  • How autoimmune disorders are driven by the adaptive immune system
  • Which factors trigger overactivation of the innate immune system resulting in an autoinflammatory condition
  • The relationship between autoimmunity and autoinflammation, with pustular psoriasis relating to autoinflammation and plaque psoriasis to autoimmunity
  • The role of the IL-36 pathway in autoinflammation compared to autoimmunity
  • Dysregulation of the IL-36 pathway leading to overexpression of IL-36
  • The further associated symptoms of GPP